Cacar Monyet vs Cacar Air
Cacar Air
Cacar air adalah infeksi kulit virus yang sangat menular
yang disebabkan oleh virus varicella-zoster milik keluarga Herpesviridae.
Infeksi primer virus varicella-zoster disebut cacar air. Reaktivasi virus di
kemudian hari menyebabkan herpes zoster (herpes zoster).
Cacar air dan cacar monyet memiliki beberapa gejala tetapi
ada beberapa perbedaan utama antara kedua penyakit ini. Beberapa perbedaan
utama (dan persamaan) antara cacar monyet dan cacar air ditabulasikan di bawah
ini;
Cacar Monyet
Monkeypox adalah penyakit zoonosis virus yang disebabkan
oleh virus monkeypox yang termasuk dalam genus Orthopoxvirus dari famili
Poxviridae. Cacar monyet biasanya muncul secara klinis dengan demam, ruam, dan
pembengkakan kelenjar getah bening dan dapat menyebabkan berbagai komplikasi
medis. Rasio kematian kasus Monkeypox adalah sekitar 3-6%.
Diagnosis banding klinis monkeypox termasuk penyakit
pembentuk ruam lainnya seperti cacar air, campak, infeksi kulit bakteri, kudis,
sifilis, dan alergi terkait pengobatan.
Monkeypox menyebabkan limfadenopati (pembengkakan kelenjar
getah bening) selama tahap prodromal penyakit, gambaran klinis ini membantu
membedakan monkeypox dari cacar air atau cacar.
Virus cacar monyet membawa banyak kesamaan dengan virus
cacar tetapi menyebabkan penyakit ringan yang sembuh sendiri. Cacar monyet
biasanya kurang menular daripada cacar.
Cacar adalah penyakit serius yang disebabkan oleh virus variola. Pada tahun 1980, Majelis Kesehatan Dunia mendeklarasikan pemberantasan cacar dari penyakit cacar. Satu-satunya sisa virus ini adalah stok yang disimpan di Pusat Pengendalian dan Pencegahan Penyakit (AS) dan di Pusat Penelitian Negara Virologi dan Bioteknologi (Rusia).
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Monkeypox |
Chickenpox |
Etiological agent |
Monkeypox is caused by the monkeypox virus, a
member of the Orthopoxvirus genus in the family Poxviridae. |
Chickenpox is caused by the varicella-zoster
virus, one of the members of the Herpesvirus family. |
Host |
Monkeypox
is a viral zoonotic disease. Animal hosts include a range of
rodents and non-human primates. |
Non-zoonotic |
Transmission |
Humans get monkeypox through close contact with an
infected person or animal (such as contact with lesions, body fluids, or
respiratory droplets), or with material contaminated with the virus such as
bedding. |
Transmission of chickenpox occurs via droplets, aerosols,
or direct contact with respiratory secretions of infected individuals. |
Structure
of the virus |
An
enveloped double-stranded DNA virus |
An
enveloped double-stranded DNA virus |
Disease prevalence |
Rare |
Common |
Incubation
period |
The
incubation period of monkeypox is usually from 6 to 13 days but can range
from 5 to 21 days. |
10-21
days |
Distribution of rash |
Monkeypox rash tends to be more concentrated on the face
and extremities rather than on the trunk. |
The rash in chickenpox is denser over the trunk and almost
never found on the palms or soles (centripetal distribution of rashes). |
Appearance
of rash |
Monkeypox
rash evolves sequentially from macules (lesions with a flat base) to papules
(slightly raised firm lesions), vesicles (lesions filled with clear fluid),
pustules (lesions filled with yellowish fluid), and crusts that dry up and
fall off. |
Chickenpox
rashes appear in multiple crops such as maculopapular, vesicles (fluid-filled
blisters), and scabs can be found in one area at the same time. The vesicle
is surrounded by an erythematous halo that has been poetically described as a
“dewdrop on a rose petal”. |
Laboratory Diagnosis |
Detection of monkeypox virus from skin lesions (vesicles
and pustules, and dry crusts) using Polymerase chain reaction (PCR). |
Detection of VZV in skin lesions (vesicles, scabs,
maculopapular lesions) using polymerase
chain reaction (PCR). |
Case
fatality rate |
The
case fatality ratio (CFR) of monkeypox has historically ranged from 0 to 11 %
in the general population. Currently, the CFR has been around 3-6%. |
The
fatality rate for varicella was approximately 1 per 100,000 cases among
children aged 1 through 14 years. |
Vaccine |
Smallpox vaccination is 85% effective at preventing
monkeypox. Prior smallpox vaccination may result in milder illness. |
Varicella vaccine is available to prevent chickenpox. Two
doses of chickenpox vaccines are 90% effective at preventing chickenpox. |
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